[11] IA Sud América 1-1 Peñarol [4] 2021-08-22 18:00
Stadium: Jardines Del Hipódromo Round: 15
Referee: Javier Burgos Home Manager: Claudio Biaggio Away Manager: Mauricio Larriera
Head to Head
| Uruguay Clausura | 2017/11/08 23:00 | IA Sud América v Peñarol | L | 2-3 |
| Uruguay Apertura | 2017/04/01 20:00 | Peñarol v IA Sud América | L | 4-0 |
| Uruguay Apertura | 2016/10/29 19:00 | IA Sud América v Peñarol | L | 1-4 |
| Uruguay Clausura | 2016/03/05 23:00 | Peñarol v IA Sud América | D | 1-1 |
| Uruguay Apertura | 2015/09/13 21:30 | IA Sud América v Peñarol | L | 1-4 |
| Uruguay Clausura | 2015/03/21 19:00 | IA Sud América v Peñarol | W | 1-0 |
| Uruguay Apertura | 2014/09/12 22:00 | Peñarol v IA Sud América | D | 1-1 |
Home History
| Uruguay Apertura | 2021/08/14 14:00 | Rentistas v IA Sud América | W | 1-2 |
| Uruguay Apertura | 2021/08/09 15:45 | IA Sud América v Montevideo Wanderers | W | 1-0 |
| Uruguay Apertura | 2021/07/31 18:00 | Boston River v IA Sud América | L | 2-0 |
| Uruguay Apertura | 2021/07/24 18:00 | IA Sud América v Atlético Fénix Montevideo | D | 1-1 |
| Uruguay Apertura | 2021/07/10 18:00 | Plaza Colonia v IA Sud América | L | 1-0 |
| Uruguay Apertura | 2021/07/04 15:00 | Deportivo Maldonado v IA Sud América | W | 1-3 |
| Uruguay Apertura | 2021/06/29 18:00 | IA Sud América v Club Atlético Progreso | L | 2-4 |
| Uruguay Apertura | 2021/06/22 20:15 | Cerro Largo v IA Sud América | L | 2-1 |
Away History
| Copa Sudamericana | 2021/08/18 22:15 | Peñarol v Sporting Cristal | W | 1-0 |
| Uruguay Apertura | 2021/08/14 22:00 | Peñarol v Club Atlético Progreso | W | 1-0 |
| Copa Sudamericana | 2021/08/11 22:15 | Sporting Cristal v Peñarol | W | 1-3 |
| Uruguay Apertura | 2021/08/06 21:00 | Cerro Largo v Peñarol | W | 0-1 |
| Uruguay Apertura | 2021/08/01 21:00 | Peñarol v CA River Plate | W | 2-0 |
| Uruguay Apertura | 2021/07/25 18:00 | Liverpool Montevideo v Peñarol | D | 3-3 |
| Copa Sudamericana | 2021/07/23 00:30 | Peñarol v Nacional de Football | L | 0-1 |
| Copa Sudamericana | 2021/07/16 00:30 | Nacional de Football v Peñarol | W | 1-2 |