| Guatemala Liga Nacional - naised | 2022/09/25 17:00 | Club Deportivo Xela - naised v CSD Concepción - naised | W | 4-0 |
| Guatemala Liga Nacional - naised | 2022/09/18 16:00 | CSD Municipal - naised v Club Deportivo Xela - naised | D | 0-0 |
| Guatemala Liga Nacional - naised | 2022/09/11 19:00 | Club Deportivo Xela - naised v Deportivo Mixco - naised | W | 5-1 |
| Guatemala Liga Nacional - naised | 2022/08/28 19:00 | Club Deportivo Xela - naised v Suchitepéquez - naised | W | 1-0 |
| Guatemala Liga Nacional - naised | 2022/06/19 17:00 | Suchitepéquez - naised v Club Deportivo Xela - naised | L | 4-3 |
| Guatemala Liga Nacional - naised | 2022/06/05 16:30 | UNIFUT Antigua Women v Club Deportivo Xela - naised | D | 1-1 |
| Guatemala Liga Nacional - naised | 2022/05/22 19:00 | Club Deportivo Xela - naised v FC Cremas - naised | W | 3-1 |
| Guatemala Liga Nacional - naised | 2022/04/24 19:00 | Club Deportivo Xela - naised v Xinabajul - naised | W | 4-0 |
| Guatemala Liga Nacional - naised | 2022/09/18 16:00 | FC Cremas - naised v Antigua GFC - naised | L | 3-1 |
| Guatemala Liga Nacional - naised | 2022/08/28 16:00 | Antigua GFC - naised v CSD Municipal - naised | L | 0-4 |
| Guatemala Liga Nacional - naised | 2022/06/05 16:00 | Antigua GFC - naised v FC Moralense Naised | L | 0-1 |
| Guatemala Liga Nacional - naised | 2022/05/29 16:00 | Antigua GFC - naised v Deportivo Mixco - naised | W | 3-1 |
| Guatemala Liga Nacional - naised | 2022/05/22 21:00 | Deportivo Mixco - naised v Antigua GFC - naised | W | 1-3 |
| Guatemala Liga Nacional - naised | 2022/05/15 16:00 | Antigua GFC - naised v FCF El Estor - naised | W | 2-0 |
| Guatemala Liga Nacional - naised | 2022/05/08 21:00 | FCF El Estor - naised v Antigua GFC - naised | W | 0-1 |
| Guatemala Liga Nacional - naised | 2022/04/10 17:00 | K’iche FC – naised v Antigua GFC - naised | W | 0-1 |