Stadium: Roy Kidd Stadium Round: 1
Home Manager: Walt Wells Away Manager: Tre Lamb
| NCAAF | 2022/11/19 17:00 | North Carolina A&T v Gardner Webb | W | 17-38 |
| NCAAF | 2022/11/12 18:00 | Gardner Webb v Campbell | W | 42-35 |
| NCAAF | 2022/10/29 17:30 | Bryant v Gardner Webb | W | 40-48 |
| NCAAF | 2022/10/22 22:00 | Gardner Webb v Charleston Southern | W | 28-14 |
| NCAAF | 2022/10/15 19:30 | Gardner Webb v Liberty | L | 20-21 |
| NCAAF | 2022/10/08 16:00 | Gardner Webb v Robert Morris | W | 48-0 |
| NCAAF | 2022/10/01 19:30 | Gardner Webb v Marshall | L | 7-28 |
| NCAAF | 2022/09/24 22:00 | Mercer v Gardner Webb | L | 45-14 |
| NCAAF | 2022/11/19 20:00 | Kennesaw State v Eastern Kentucky | W | 38-45 |
| NCAAF | 2022/11/12 19:00 | Eastern Kentucky v Jacksonville State | L | 17-42 |
| NCAAF | 2022/11/05 21:00 | Central Arkansas v Eastern Kentucky | W | 14-42 |
| NCAAF | 2022/10/29 18:00 | Eastern Kentucky v SE Missouri St | W | 28-23 |
| NCAAF | 2022/10/22 19:00 | North Alabama v Eastern Kentucky | W | 53-56 |
| NCAAF | 2022/10/15 22:00 | Sam Houston State v Eastern Kentucky | L | 25-17 |
| NCAAF | 2022/10/01 22:00 | Southern Utah v Eastern Kentucky | W | 28-35 |
| NCAAF | 2022/09/24 20:00 | Eastern Kentucky v Austin Peay | L | 20-31 |