[79] Northwestern 7-33 Michigan [7] 2021-10-23 16:00
Stadium: Michigan Stadium Round: 1
Home Manager: Jim Harbaugh Away Manager: Pat Fitzgerald
Head to Head
| NCAAF | 2018/09/29 20:30 | Michigan v Northwestern | L | 20-17 |
| NCAAF | 2015/10/10 19:30 | Michigan v Northwestern | L | 38-0 |
| NCAAF | 2014/11/08 20:30 | Northwestern v Michigan | L | 9-10 |
| NCAAF | 2012/11/10 12:00 | Michigan v Northwestern | L | 38-31 |
| NCAAF | 2011/10/08 12:00 | Northwestern v Michigan | L | 24-42 |
| NCAAF | 2008/11/15 12:00 | Michigan v Northwestern | W | 14-21 |
| NCAAF | 2007/09/29 12:00 | Northwestern v Michigan | L | 16-28 |
| NCAAF | 2006/10/28 12:00 | Michigan v Northwestern | L | 17-3 |
| NCAAF | 2005/10/29 12:00 | Northwestern v Michigan | L | 17-33 |
| NCAAF | 2004/11/13 12:00 | Michigan v Northwestern | L | 42-20 |
| NCAAF | 2003/11/15 12:00 | Northwestern v Michigan | L | 10-41 |
| NCAAF | 2000/11/04 12:00 | Northwestern v Michigan | W | 54-51 |