| NIT - naised | 03/21 23:00 | 122 | Coll Of Charleston - naised v USC Upstate - naised | L | 78-60 | |
| WNCAAB | 03/10 01:00 | 2 | [230] Radford - naised v USC Upstate - naised [185] | L | 61-45 | |
| WNCAAB | 03/07 23:00 | 3 | USC Upstate - naised v Longwood - naised | W | 60-37 | |
| WNCAAB | 02/28 23:30 | - | Presbyterian - naised v USC Upstate - naised | L | 47-43 | |
| WNCAAB | 02/24 21:00 | - | USC Upstate - naised v Winthrop - naised | L | 61-67 | |
| WNCAAB | 02/21 23:00 | - | Charleston Southern - naised v USC Upstate - naised | L | 66-59 | |
| WNCAAB | 02/17 19:00 | - | USC Upstate - naised v Gardner Webb - naised | W | 73-56 | |
| WNCAAB | 02/15 00:00 | - | USC Upstate - naised v High Point - naised | L | 50-53 | |
| WNCAAB | 02/10 18:00 | - | [150] USC Upstate - naised v UNC Asheville - naised [250] | W | 71-65 | |
| WNCAAB | 02/08 00:00 | - | USC Upstate - naised v Longwood - naised | W | 49-45 | |
| WNCAAB | 02/03 19:00 | - | Radford - naised v USC Upstate - naised | L | 67-61 | |
| WNCAAB | 02/01 00:00 | - | USC Upstate - naised v Presbyterian - naised | W | 62-58 | |
| WNCAAB | 01/27 18:00 | - | Gardner Webb - naised v USC Upstate - naised | W | 59-78 | |
| WNCAAB | 01/25 00:00 | - | High Point - naised v USC Upstate - naised | W | 49-59 | |
| WNCAAB | 01/20 21:00 | - | USC Upstate - naised v Radford - naised | W | 65-60 | |
| WNCAAB | 01/18 00:00 | - | Longwood - naised v USC Upstate - naised | L | 66-58 | |
| WNCAAB | 01/13 21:00 | - | USC Upstate - naised v Charleston Southern - naised | W | 59-58 | |
| WNCAAB | 01/06 19:00 | - | Winthrop - naised v USC Upstate - naised | W | 51-52 | |
| WNCAAB | 01/04 00:00 | - | USC Upstate - naised v UNC Asheville - naised | W | 71-44 | |
| WNCAAB | 12/20 19:00 | - | [242] USC Upstate - naised v Georgia Tech - naised [81] | L | 50-81 | |
| WNCAAB | 12/18 16:00 | - | [77] UNC Greensboro - naised v USC Upstate - naised [219] | L | 56-53 | |
| WNCAAB | 12/09 21:30 | - | [128] Furman - naised v USC Upstate - naised [246] | W | 58-61 | |
| WNCAAB | 12/05 16:30 | - | [281] USC Upstate - naised v Western Carolina - naised [305] | W | 73-64 | |
| WNCAAB | 11/30 22:30 | - | [255] USC Upstate - naised v Samford - naised [143] | L | 52-57 | |
| WNCAAB | 11/25 19:00 | - | [320] North Florida - naised v USC Upstate - naised [302] | W | 60-73 | |
| WNCAAB | 11/24 19:00 | - | [152] Detroit Mercy - naised v USC Upstate - naised [288] | L | 71-64 | |
| WNCAAB | 11/21 00:00 | - | [347] South Carolina State - naised v USC Upstate - naised [318] | W | 53-58 | |
| WNCAAB | 11/17 17:00 | - | USC Upstate - naised v Queens - naised | L | 51-61 | |
| WNCAAB | 11/15 00:00 | - | USC Upstate - naised v AZS CMUJ Krakow - naised | W | 72-44 | |
| WNCAAB | 11/11 23:00 | - | [350] USC Upstate - naised v Kentucky - naised [141] | L | 54-82 |