| WNCAAB | 03/02 19:00 | 1 | Radford - naised v USC Upstate - naised | L | 55-43 | |
| WNCAAB | 02/26 23:00 | 1 | Winthrop - naised v USC Upstate - naised | W | 49-58 | |
| WNCAAB | 02/23 19:00 | 1 | UNC Asheville - naised v USC Upstate - naised | L | 56-53 | |
| WNCAAB | 02/19 23:00 | 1 | USC Upstate - naised v Presbyterian - naised | L | 58-66 | |
| WNCAAB | 02/13 00:00 | 1 | Longwood - naised v USC Upstate - naised | L | 80-58 | |
| WNCAAB | 02/09 20:00 | 1 | Charleston Southern - naised v USC Upstate - naised | L | 74-62 | |
| WNCAAB | 02/06 00:00 | 1 | Campbell - naised v USC Upstate - naised | L | 61-41 | |
| WNCAAB | 02/02 19:00 | 1 | USC Upstate - naised v Radford - naised | L | 41-82 | |
| WNCAAB | 01/30 00:00 | 1 | Hampton - naised v USC Upstate - naised | L | 67-43 | |
| WNCAAB | 01/26 19:00 | 1 | USC Upstate - naised v Longwood - naised | W | 72-67 | |
| WNCAAB | 01/22 23:00 | 1 | Gardner Webb - naised v USC Upstate - naised | L | 92-72 | |
| WNCAAB | 01/19 19:00 | 1 | USC Upstate - naised v Charleston Southern - naised | L | 75-78 | |
| WNCAAB | 01/15 23:00 | 1 | USC Upstate - naised v UNC Asheville - naised | L | 86-93 | |
| WNCAAB | 01/12 19:00 | 1 | Presbyterian - naised v USC Upstate - naised | L | 70-54 | |
| WNCAAB | 01/11 00:00 | 1 | USC Upstate - naised v Winthrop - naised | W | 76-50 | |
| WNCAAB | 01/05 19:00 | 1 | USC Upstate - naised v High Point - naised | L | 61-87 | |
| WNCAAB | 12/18 23:00 | 1 | USC Upstate - naised v Brevard - naised | W | 71-53 | |
| WNCAAB | 12/16 19:00 | 1 | East Carolina - naised v USC Upstate - naised | L | 63-53 | |
| WNCAAB | 12/08 19:00 | 1 | USC Upstate - naised v Bob Jones Bruins Women | W | 101-53 | |
| WNCAAB | 12/04 17:00 | 1 | Western Carolina - naised v USC Upstate - naised | L | 68-64 | |
| WNCAAB | 11/28 23:00 | 1 | South Carolina State - naised v USC Upstate - naised | L | 71-66 | |
| WNCAAB | 11/24 20:00 | 1 | North Carolina Central - naised v USC Upstate - naised | W | 63-82 | |
| WNCAAB | 11/17 19:00 | 1 | Furman - naised v USC Upstate - naised | L | 78-67 | |
| WNCAAB | 11/13 23:00 | 1 | USC Upstate - naised v Converse - naised | W | 69-51 | |
| WNCAAB | 11/11 17:00 | 1 | Nebraska - naised v USC Upstate - naised | L | 87-64 | |
| WNCAAB | 11/10 01:00 | 1 | Nebraska Omaha - naised v USC Upstate - naised | L | 96-69 | |
| WNCAAB | 11/07 00:00 | 1 | Virginia Tech - naised v USC Upstate - naised | L | 96-45 | |
| WNCAAB | 03/03 01:00 | 1 | Lipscomb - naised v USC Upstate - naised | L | 95-53 | |
| WNCAAB | 02/24 18:00 | 1 | USC Upstate - naised v NJIT - naised | W | 74-67 | |
| WNCAAB | 02/20 00:00 | 1 | North Florida - naised v USC Upstate - naised | L | 79-61 |